Opportunity Information: Apply for PA 17 106
The National Institutes of Health (NIH) announced this discretionary grant opportunity, PA-17-106, titled "Targeted basic behavioral and social science and intervention development for HIV prevention and care (R01)." It supports health-related research under CFDA 93.242 and uses the R01 funding mechanism, which typically backs more mature, robust projects than smaller exploratory mechanisms. A closely related announcement, PA-17-105, uses the R21 mechanism, while this one is specifically positioned for full-scale R01 studies.
The overall purpose is to fund innovative, targeted research that can reduce new HIV infections and improve health outcomes for people living with HIV. The FOA emphasizes behavioral and social science as essential drivers of HIV prevention and care, and it is designed to move research along a practical pathway: first building the foundational behavioral and social science knowledge needed to design better interventions, then translating those findings into real-world intervention components, and finally testing whether those interventions actually work.
The announcement encourages three connected types of projects. First, it calls for basic behavioral and social science research that fills key knowledge gaps relevant to HIV prevention and care. This includes research aimed at understanding behaviors, decision-making, social dynamics, structural factors, stigma, adherence challenges, health communication, and other social or psychological mechanisms that shape HIV risk and care engagement. The point is not basic science in the abstract, but basic research targeted toward questions that directly inform how interventions should be built or improved.
Second, it encourages investigators to translate and operationalize findings from those basic studies into intervention development. In practice, this means taking what is learned about behavioral and social mechanisms and turning it into intervention strategies, program elements, messages, delivery models, or implementation approaches that can realistically be used by communities and health systems. This phase also includes early-stage testing focused on acceptability and feasibility, making sure that the proposed intervention makes sense for the intended population, fits the setting, and can be delivered as designed.
Third, the FOA supports efficacy testing of HIV prevention and care interventions. This is where a developed intervention is evaluated to determine whether it produces the intended outcomes under controlled or well-structured study conditions. In the context of HIV, efficacy outcomes could include reductions in risk behaviors, improved uptake or adherence to prevention tools, stronger linkage to care, retention in care, viral suppression, improved medication adherence, or other measurable outcomes that contribute to preventing transmission and improving health.
Eligibility is broad and includes many types of U.S. and non-U.S. applicants. Eligible applicants listed include state, county, city or township governments, special district governments, and independent school districts, along with public and state-controlled institutions of higher education, private institutions of higher education, and public housing authorities/Indian housing authorities. The FOA is also open to federally recognized Native American tribal governments and other Native American tribal organizations, as well as nonprofits both with and without 501(c)(3) status. For-profit organizations (other than small businesses) and small businesses are eligible, and the announcement also notes "Others" as eligible applicants, which is reinforced by the explicit inclusion of additional organization types.
The FOA makes a point of welcoming applications from organizations that serve or represent communities often central to HIV prevention and care efforts. It explicitly lists Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and Indian/Native American Tribal Governments other than federally recognized entities. It also includes faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities or foreign organizations, signaling an openness to cross-setting and international work when relevant.
Key administrative details included in the source data are the original posting timeframe (creation date January 9, 2017) and an original closing date of January 24, 2018. The award ceiling and expected awards fields are not specified in the provided information, which typically means applicants would need to consult the full FOA text and NIH institute-specific guidance to understand budget expectations, project period norms, and the likely scale of awards.
In short, this NIH R01 opportunity is aimed at strengthening the full pipeline from targeted behavioral and social science discovery to intervention design and feasibility work, through to rigorous efficacy testing, all in service of preventing HIV transmission and improving outcomes for people living with HIV. The emphasis is on practical, intervention-relevant behavioral and social science that can be translated into programs and strategies that communities and care systems can actually use.Apply for PA 17 106
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Targeted basic behavioral and social science and intervention development for HIV prevention and care (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
- This funding opportunity was created on 2017-01-09.
- Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the official name and number of this NIH funding opportunity?
This opportunity is NIH discretionary grant announcement PA-17-106, titled "Targeted basic behavioral and social science and intervention development for HIV prevention and care (R01)."
What funding mechanism does PA-17-106 use?
PA-17-106 uses the NIH R01 funding mechanism. The R01 mechanism is generally used for more mature and robust research projects compared to smaller exploratory mechanisms.
Is there a related NIH announcement for earlier-stage or exploratory studies?
Yes. A closely related announcement is PA-17-105, which uses the R21 mechanism. PA-17-106 is positioned for full-scale R01 studies.
What is the overall goal of this FOA?
The overall purpose is to fund innovative, targeted research that can reduce new HIV infections and improve health outcomes for people living with HIV, with a strong emphasis on behavioral and social science as key drivers of HIV prevention and care.
What kinds of research does this opportunity prioritize?
The FOA prioritizes targeted behavioral and social science research that directly informs intervention development and testing for HIV prevention and care. The focus is on practical, intervention-relevant questions rather than basic science in the abstract.
What is meant by "targeted basic behavioral and social science" in this FOA?
It refers to basic behavioral and social science research designed to fill key knowledge gaps that are directly relevant to HIV prevention and care and that can be used to build or improve interventions.
What types of topics or mechanisms might be studied under the basic research focus?
Examples mentioned include behaviors, decision-making, social dynamics, structural factors, stigma, adherence challenges, health communication, and other social or psychological mechanisms that shape HIV risk and engagement in care.
Does the FOA support intervention development work?
Yes. It encourages translating findings from basic behavioral and social science into intervention strategies, program elements, messages, delivery models, or implementation approaches that can realistically be used by communities and health systems.
Does this opportunity include early-stage testing like feasibility or acceptability?
Yes. Intervention development can include early-stage testing focused on acceptability and feasibility to determine whether an intervention makes sense for the intended population, fits the setting, and can be delivered as designed.
Does the FOA support efficacy testing of interventions?
Yes. The FOA supports efficacy testing, meaning evaluation of whether a developed HIV prevention or care intervention produces intended outcomes under controlled or well-structured study conditions.
What are examples of outcomes that could be used in efficacy testing under this FOA?
Examples provided include reductions in risk behaviors; improved uptake or adherence to prevention tools; stronger linkage to care; retention in care; viral suppression; improved medication adherence; and other measurable outcomes that help prevent transmission and improve health.
How does the FOA describe the pathway from basic science to intervention impact?
The FOA emphasizes a practical pipeline: (1) build foundational behavioral and social science knowledge, (2) translate those findings into real-world intervention components and conduct feasibility/acceptability work, and (3) test whether the interventions work through efficacy testing.
What CFDA number is associated with this opportunity?
This funding opportunity supports health-related research under CFDA 93.242.
Who is eligible to apply?
Eligibility is broad and includes many U.S. and non-U.S. applicants. Eligible applicants listed include various government entities, educational institutions, tribal entities and organizations, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, and other organization types explicitly included in the announcement.
Are U.S. government entities eligible (state, county, city, etc.)?
Yes. Eligible applicants include state, county, city or township governments, special district governments, and independent school districts.
Are colleges and universities eligible?
Yes. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education.
Are tribal governments and tribal organizations eligible?
Yes. The FOA includes federally recognized Native American tribal governments and other Native American tribal organizations, and it also references Indian/Native American Tribal Governments other than federally recognized entities.
Are nonprofits eligible even if they do not have 501(c)(3) status?
Yes. The FOA states that nonprofits both with and without 501(c)(3) status are eligible.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) and small businesses are listed as eligible applicants.
Are faith-based or community-based organizations included?
Yes. The FOA explicitly includes faith-based or community-based organizations among eligible applicants.
Are U.S. territories or possessions eligible?
Yes. The FOA includes regional organizations and U.S. territories or possessions among eligible applicants.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The announcement indicates eligibility for non-domestic (non-U.S.) entities or foreign organizations, signaling openness to international work when relevant.
Does the FOA encourage applications from organizations serving populations heavily impacted by HIV?
Yes. The FOA specifically welcomes applications from organizations that serve or represent communities often central to HIV prevention and care efforts.
Which institution types are explicitly called out as welcomed?
The FOA explicitly lists Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); and Indian/Native American Tribal Governments other than federally recognized entities.
When was PA-17-106 originally posted?
The source data lists a creation date of January 9, 2017.
What was the original closing date listed for this opportunity?
The source data lists an original closing date of January 24, 2018.
Is the award ceiling (maximum award amount) provided in the information here?
No. The award ceiling field is not specified in the provided information. Applicants would typically need to consult the full FOA text and NIH institute-specific guidance for budget expectations.
Is the expected number of awards provided?
No. The expected awards field is not specified in the provided information.
Where should applicants look for budget expectations or typical project period norms?
Based on the information provided, applicants would need to consult the full FOA text and NIH institute-specific guidance to understand budget expectations, project period norms, and the likely scale of awards.
What is the key theme of the FOA in plain terms?
The central theme is strengthening the full pipeline from targeted behavioral and social science discovery, to intervention design and feasibility work, to rigorous efficacy testing, all aimed at preventing HIV transmission and improving outcomes for people living with HIV.
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