Targeted basic behavioral and social science and intervention development for HIV prevention and care (R01) | PA 17 106

Opportunity Information: Apply for PA 17 106

The National Institutes of Health (NIH) announced this discretionary grant opportunity, PA-17-106, titled "Targeted basic behavioral and social science and intervention development for HIV prevention and care (R01)." It supports health-related research under CFDA 93.242 and uses the R01 funding mechanism, which typically backs more mature, robust projects than smaller exploratory mechanisms. A closely related announcement, PA-17-105, uses the R21 mechanism, while this one is specifically positioned for full-scale R01 studies.

The overall purpose is to fund innovative, targeted research that can reduce new HIV infections and improve health outcomes for people living with HIV. The FOA emphasizes behavioral and social science as essential drivers of HIV prevention and care, and it is designed to move research along a practical pathway: first building the foundational behavioral and social science knowledge needed to design better interventions, then translating those findings into real-world intervention components, and finally testing whether those interventions actually work.

The announcement encourages three connected types of projects. First, it calls for basic behavioral and social science research that fills key knowledge gaps relevant to HIV prevention and care. This includes research aimed at understanding behaviors, decision-making, social dynamics, structural factors, stigma, adherence challenges, health communication, and other social or psychological mechanisms that shape HIV risk and care engagement. The point is not basic science in the abstract, but basic research targeted toward questions that directly inform how interventions should be built or improved.

Second, it encourages investigators to translate and operationalize findings from those basic studies into intervention development. In practice, this means taking what is learned about behavioral and social mechanisms and turning it into intervention strategies, program elements, messages, delivery models, or implementation approaches that can realistically be used by communities and health systems. This phase also includes early-stage testing focused on acceptability and feasibility, making sure that the proposed intervention makes sense for the intended population, fits the setting, and can be delivered as designed.

Third, the FOA supports efficacy testing of HIV prevention and care interventions. This is where a developed intervention is evaluated to determine whether it produces the intended outcomes under controlled or well-structured study conditions. In the context of HIV, efficacy outcomes could include reductions in risk behaviors, improved uptake or adherence to prevention tools, stronger linkage to care, retention in care, viral suppression, improved medication adherence, or other measurable outcomes that contribute to preventing transmission and improving health.

Eligibility is broad and includes many types of U.S. and non-U.S. applicants. Eligible applicants listed include state, county, city or township governments, special district governments, and independent school districts, along with public and state-controlled institutions of higher education, private institutions of higher education, and public housing authorities/Indian housing authorities. The FOA is also open to federally recognized Native American tribal governments and other Native American tribal organizations, as well as nonprofits both with and without 501(c)(3) status. For-profit organizations (other than small businesses) and small businesses are eligible, and the announcement also notes "Others" as eligible applicants, which is reinforced by the explicit inclusion of additional organization types.

The FOA makes a point of welcoming applications from organizations that serve or represent communities often central to HIV prevention and care efforts. It explicitly lists Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and Indian/Native American Tribal Governments other than federally recognized entities. It also includes faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities or foreign organizations, signaling an openness to cross-setting and international work when relevant.

Key administrative details included in the source data are the original posting timeframe (creation date January 9, 2017) and an original closing date of January 24, 2018. The award ceiling and expected awards fields are not specified in the provided information, which typically means applicants would need to consult the full FOA text and NIH institute-specific guidance to understand budget expectations, project period norms, and the likely scale of awards.

In short, this NIH R01 opportunity is aimed at strengthening the full pipeline from targeted behavioral and social science discovery to intervention design and feasibility work, through to rigorous efficacy testing, all in service of preventing HIV transmission and improving outcomes for people living with HIV. The emphasis is on practical, intervention-relevant behavioral and social science that can be translated into programs and strategies that communities and care systems can actually use.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Targeted basic behavioral and social science and intervention development for HIV prevention and care (R01)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
• This funding opportunity was created on 2017-01-09.
• Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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