Opportunity Information: Apply for PAR 23 282
The NIAID Research Education Program Advancing the Careers of a Diverse Research Workforce (R25 Clinical Trial Not Allowed) is a National Institutes of Health (NIH) funding opportunity designed to build and strengthen research education programs that help develop the next generation of biomedical and behavioral researchers. The central purpose is workforce development, with a strong emphasis on expanding participation and advancement of individuals from diverse backgrounds, including groups that are underrepresented in biomedical and behavioral sciences. Rather than funding a traditional hypothesis-driven research project, this R25 mechanism supports structured educational and career-development activities that prepare participants to pursue additional training, graduate or professional study, and long-term research careers aligned with NIH and NIAID mission areas.
This opportunity specifically supports research education activities that are organized around several core program elements. First, it can fund courses for skills development, which typically include structured instruction in research methods, responsible conduct of research, quantitative and computational skills, scientific communication, grant writing, and other competencies that improve research readiness and competitiveness. Second, it supports research experiences, meaning hands-on, mentored exposure to research environments where participants can develop practical skills, learn how research teams function, and build a record of research engagement. Third, it supports mentoring activities, which can include formal mentoring networks, career coaching, near-peer mentoring, mentorship training for faculty, and structured guidance that helps participants navigate academic and research career pathways. Overall, the emphasis is on creating a coherent education and mentoring framework that measurably supports progression into research training and research careers.
A key administrative boundary is that clinical trials are not allowed under this notice of funding opportunity. In practical terms, the proposed program cannot include conducting clinical trials as part of the supported activities. Applicants should structure research experiences and educational content accordingly, focusing on training, education, and non-trial research exposure rather than interventional clinical study implementation.
Eligibility is broad across many U.S.-based organization types, reflecting the goal of reaching participants through multiple institutional settings. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; and a range of nonprofit organizations (both with and without 501(c)(3) status) as long as they are not institutions of higher education when applying under those nonprofit categories. For-profit organizations (other than small businesses) and small businesses are also listed as eligible, along with Native American tribal governments (federally recognized), public housing authorities/Indian housing authorities, and tribal organizations other than federally recognized tribal governments. The announcement also highlights additional eligible applicant categories that often play a major role in broadening participation, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
At the same time, there are clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities or foreign institutions are not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. These restrictions mean the applicant organization and supported program activities must be structured without foreign components in the NIH sense, and applicants should be careful about overseas sites, subawards, or program elements that could be interpreted as foreign components.
From a funding and administrative standpoint, this is an NIH discretionary grant mechanism under the R25 Research Education Program authority, with the activity category listed as Health and the CFDA number 93.855. The opportunity number is PAR-23-282, and the agency is NIH (with NIAID as the sponsoring institute for this program). The opportunity lists an award ceiling of $351,000. The original closing date shown is 2026-09-07. The notice was created on 2023-11-03. The listing also shows the expected number of awards field without a specified value in the provided source data, which typically means applicants should not assume a particular award volume and should instead focus on responsiveness, quality, feasibility, and alignment with the program goals.
In short, this grant opportunity is aimed at institutions and organizations that want to build or enhance structured research education programs that combine skills-based coursework, meaningful research exposure, and strong mentoring to help a more diverse group of trainees and early-career participants move into and persist in research pathways. The intended outcome is a stronger, more inclusive biomedical and behavioral research workforce, achieved through education and career development programming rather than through funding clinical trials or stand-alone research projects.Apply for PAR 23 282
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIAID Research Education Program Advancing the Careers of a Diverse Research Workforce (R25 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
- This funding opportunity was created on 2023-11-03.
- Applicants must submit their applications by 2026-09-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $351,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is this funding opportunity?
The NIAID Research Education Program Advancing the Careers of a Diverse Research Workforce (R25 Clinical Trial Not Allowed) is an NIH funding opportunity (R25 mechanism) to build or strengthen structured research education programs. The focus is workforce development: preparing the next generation of biomedical and behavioral researchers through education, research exposure, and mentoring, rather than funding a traditional hypothesis-driven research project.
What is the central purpose of the program?
The central purpose is to develop and strengthen the biomedical and behavioral research workforce. The program emphasizes education and career development activities that measurably help participants progress into additional training, graduate or professional study, and long-term research careers aligned with NIH and NIAID mission areas.
Who is the sponsoring agency and institute?
The sponsoring agency is the National Institutes of Health (NIH), with the National Institute of Allergy and Infectious Diseases (NIAID) as the sponsoring institute for this program.
What is the opportunity number?
The opportunity number is PAR-23-282.
What type of grant mechanism is this?
This is an NIH discretionary grant under the R25 Research Education Program authority.
What kinds of activities does this R25 program support?
The opportunity supports structured research education activities organized around core elements that can include:
- Courses for skills development (for example, research methods, responsible conduct of research, quantitative and computational skills, scientific communication, and grant writing)
- Research experiences (hands-on, mentored exposure to research environments to build practical skills and research engagement)
- Mentoring activities (formal mentoring networks, career coaching, near-peer mentoring, mentorship training for faculty, and structured career guidance)
The overall emphasis is a coherent education and mentoring framework that supports participant progression into research training and research careers.
Does this opportunity fund a traditional research project?
No. This R25 mechanism is described as supporting structured educational and career-development activities rather than a stand-alone, hypothesis-driven research project.
Are clinical trials allowed under this opportunity?
No. Clinical trials are not allowed under this notice of funding opportunity. Program activities must be designed so they do not include conducting clinical trials.
What does “Clinical Trial Not Allowed” mean in practice for program design?
It means the supported program cannot include the conduct of clinical trials as part of its activities. Applicants should structure research experiences and educational content around training, education, and non-trial research exposure rather than implementation of interventional clinical studies.
What is the emphasis regarding diversity in the research workforce?
A strong emphasis is placed on expanding participation and advancement of individuals from diverse backgrounds, including groups underrepresented in biomedical and behavioral sciences. The program is specifically framed around advancing careers and broadening participation through education and mentoring.
Who can apply (in general terms)?
Eligibility is broad across many U.S.-based organizations, reflecting the goal of reaching participants through multiple institutional settings. Eligible applicants include various government entities, educational institutions, nonprofit organizations, for-profit organizations (including small businesses), tribal entities, public housing authorities/Indian housing authorities, eligible federal agencies, and U.S. territories or possessions.
Which government entities are eligible to apply?
Eligible government applicants include state governments, county governments, city or township governments, and special district governments.
Are institutions of higher education eligible?
Yes. Public and state-controlled institutions of higher education and private institutions of higher education are listed as eligible applicants.
Are nonprofit organizations eligible?
Yes. The opportunity lists nonprofit organizations with 501(c)(3) status and nonprofit organizations without 501(c)(3) status as eligible, as long as they are not institutions of higher education when applying under those nonprofit categories.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) and small businesses are listed as eligible.
Are tribal entities eligible?
Yes. Native American tribal governments (federally recognized) are eligible, as are tribal organizations other than federally recognized tribal governments.
Are public housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities are listed as eligible applicants.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included among eligible applicant types.
Are there highlighted institution types that may be particularly relevant to broadening participation?
Yes. The announcement highlights categories that often play a major role in broadening participation, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also notes faith-based or community-based organizations and regional organizations as eligible categories.
Can non-U.S. (foreign) organizations apply?
No. Non-domestic (non-U.S.) entities or foreign institutions are not eligible to apply.
Can a U.S. organization apply if it has a non-domestic component?
No. Non-domestic components of U.S. organizations are not eligible to apply under this opportunity.
Are foreign components allowed in the project?
No. Foreign components (as defined by the NIH Grants Policy Statement) are not allowed.
What do the foreign restrictions mean for program structure?
They mean the applicant organization and supported program activities must be structured without foreign components in the NIH sense. Applicants should be cautious about overseas sites, subawards, or program elements that could be interpreted as foreign components.
What is the award ceiling listed for this opportunity?
The opportunity lists an award ceiling of $351,000.
When is the closing date shown in the listing?
The original closing date shown is 2026-09-07.
When was this opportunity listing created?
The notice was created on 2023-11-03.
How many awards will be made?
The provided listing shows the expected number of awards field without a specified value. Based on the provided information alone, applicants should not assume a particular number of awards and should focus on responsiveness, quality, feasibility, and alignment with program goals.
What is the CFDA number and activity category?
The CFDA number is 93.855, and the activity category is listed as Health.
What outcomes is the program intended to achieve?
The intended outcome is a stronger, more inclusive biomedical and behavioral research workforce. This is expected to be achieved through education and career development programming that combines skills-based coursework, meaningful research exposure, and strong mentoring to support participant progression into research pathways.
What is the best way to describe the overall program focus?
This opportunity is designed for organizations that want to create or enhance a structured research education program that prepares participants for research careers, with an emphasis on advancing the careers of individuals from diverse and underrepresented backgrounds, and with the clear boundary that clinical trials are not part of the supported activities.
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