Opportunity Information: Apply for PAR 23 054
The National Institutes of Health (NIH) funding opportunity PAR-23-054, titled "Advanced-Stage Development and Utilization of Research Infrastructure for Interdisciplinary Aging Studies (R33 Clinical Trial Optional)," supports projects that build or strengthen research infrastructure designed to move the science of aging forward. The central emphasis is on infrastructure that is both novel and ready for advanced-stage development and use, especially where progress depends on interdisciplinary partnerships or multi-sector collaborations. In practical terms, this opportunity is meant for applicants who are proposing to create, expand, or enhance shared resources, platforms, tools, networks, or coordinated capabilities that enable better aging research than what individual labs or single disciplines could accomplish alone. Clinical trials may be included, but they are optional rather than required.
This is a discretionary NIH grant mechanism using the R33 funding instrument, which generally aligns with later-stage development, refinement, and implementation of a resource or capability that is sufficiently mature to be put to work by a broader research community. The intent is not simply to fund another individual research project, but to invest in infrastructure that can catalyze multiple studies, accelerate discovery, and support cross-cutting approaches in aging research. The focus on interdisciplinary aging studies signals that proposed infrastructure should help connect methods, data, and expertise across fields (for example, linking biology of aging with behavioral science, clinical research, population studies, technology development, or health services research), particularly in areas where the field needs coordinated capacity to make meaningful advances.
Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other eligible entities. The FOA explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. This broad eligibility reflects NIH interest in encouraging wide participation and ensuring that infrastructure for aging research can be developed in diverse settings, including those that serve populations often underrepresented in biomedical research.
Foreign participation is restricted in specific ways. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) institutions are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components are allowed as defined in the NIH Grants Policy Statement, meaning a U.S. applicant may include certain foreign activities or collaborations when they meet NIH policy definitions and are appropriately justified. In short, the application must be anchored by an eligible U.S.-based applicant organization, but international collaboration can still be possible through allowable foreign components.
Key administrative details provided for this opportunity include an original closing date of 2025-12-02 and an award ceiling of $500,000. The opportunity is associated with CFDA numbers 93.313 and 93.866 and was created on 2022-11-21. While the posted information does not specify the expected number of awards, the ceiling indicates the maximum total award amount under the listing as provided. Applicants interested in pursuing this FOA should plan proposals around infrastructure development and utilization that clearly enables interdisciplinary aging research, demonstrate why the infrastructure is needed and how it will be used, and show how collaborations or partnerships will be structured to deliver broad value to the aging research community.Apply for PAR 23 054
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Advanced-Stage Development and Utilization of Research Infrastructure for Interdisciplinary Aging Studies (R33 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.313, 93.866.
- This funding opportunity was created on 2022-11-21.
- Applicants must submit their applications by 2025-12-02. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NIH PAR-23-054 (R33) Advanced-Stage Research Infrastructure for Interdisciplinary Aging Studies
What is the NIH funding opportunity PAR-23-054?
PAR-23-054 is a National Institutes of Health (NIH) funding opportunity titled "Advanced-Stage Development and Utilization of Research Infrastructure for Interdisciplinary Aging Studies (R33 Clinical Trial Optional)." It supports projects focused on building or strengthening research infrastructure that advances the science of aging, particularly where success depends on interdisciplinary partnerships or multi-sector collaborations.
What is the main goal of this opportunity?
The main goal is to invest in shared infrastructure that can catalyze multiple aging-related studies, accelerate discovery, and enable cross-cutting approaches that single labs or single disciplines typically cannot achieve on their own.
What kinds of projects does this FOA support?
This FOA supports proposals to create, expand, or enhance shared resources, platforms, tools, networks, or coordinated capabilities that enable stronger interdisciplinary aging research.
Is this opportunity meant to fund a single research study?
No. The emphasis is on infrastructure rather than funding another standalone individual research project. The intended impact is broader: infrastructure that supports multiple studies and a wider research community.
What does "research infrastructure" mean in the context of this FOA?
Based on the description provided, research infrastructure can include shared resources, platforms, tools, networks, or coordinated capabilities that help researchers work across disciplines and sectors to advance aging research.
What does "advanced-stage development" imply for proposed infrastructure?
It implies the infrastructure should be novel and sufficiently mature to be ready for later-stage development, refinement, and implementation so it can be used by a broader research community.
What is the funding mechanism used for PAR-23-054?
This is a discretionary NIH grant mechanism using the R33 funding instrument, generally aligned with later-stage development, refinement, and implementation of a mature resource or capability.
Are clinical trials required under this FOA?
No. Clinical trials may be included, but they are optional rather than required ("Clinical Trial Optional").
What does "interdisciplinary aging studies" mean here?
It signals that the proposed infrastructure should connect methods, data, and expertise across fields relevant to aging research. Examples mentioned include linking biology of aging with behavioral science, clinical research, population studies, technology development, or health services research.
Why does the FOA emphasize interdisciplinary partnerships and multi-sector collaborations?
The FOA emphasizes these collaborations because the targeted infrastructure is intended to enable progress that depends on coordinated capacity and expertise that spans disciplines and, in some cases, sectors.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S.-based organizations and governmental entities, including state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; and Native American tribal organizations that are not federally recognized tribal governments.
Are nonprofits eligible to apply?
Yes. Nonprofit organizations with or without 501(c)(3) status are eligible to apply, as long as they are not institutions of higher education.
Are for-profit organizations eligible to apply?
Yes. For-profit organizations (other than small businesses) are eligible, and small businesses are also eligible.
Are public housing authorities eligible to apply?
Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.
Does the FOA highlight any additional categories of eligible applicants?
Yes. The FOA explicitly highlights Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISI); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; and U.S. territories or possessions.
Are non-U.S. (foreign) organizations eligible to apply as the applicant?
No. Non-domestic (non-U.S.) entities and non-domestic (non-U.S.) institutions are not eligible to apply as the applicant organization.
Can a U.S. organization with a non-U.S. component apply?
Non-domestic components of U.S. organizations are not eligible to apply. The application must be anchored by an eligible U.S.-based applicant organization.
Is international collaboration allowed at all?
Yes, in limited form. Foreign components are allowed as defined in the NIH Grants Policy Statement. A U.S. applicant may include certain foreign activities or collaborations when they meet NIH policy definitions and are appropriately justified.
What is the closing date for this opportunity?
The information provided lists an original closing date of 2025-12-02.
What is the award ceiling?
The award ceiling listed is $500,000. This indicates the maximum total award amount under the listing as provided.
How many awards will NIH make under this FOA?
The posted information does not specify the expected number of awards.
What CFDA numbers are associated with this opportunity?
The opportunity is associated with CFDA numbers 93.313 and 93.866.
When was this funding opportunity created?
The opportunity was created on 2022-11-21.
What should applicants emphasize in their proposals based on the information provided?
Applicants should center proposals on infrastructure development and utilization that clearly enables interdisciplinary aging research, explain why the infrastructure is needed and how it will be used, and describe how collaborations or partnerships will be structured to deliver broad value to the aging research community.
What kinds of outcomes is NIH trying to enable with this infrastructure?
The described intent is to accelerate discovery, support cross-cutting approaches in aging research, and create infrastructure that can serve multiple studies and a broader research community.
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